Background and objectives: The surgical removal of thyroid specimen in thyroid lesion is fairly common and constitutes one of the routinely encountered specimens in most of the histopathology laboratories. The aim of the study was to determine the various morphological types of neoplastic and nonneo plastic lesions among the thyroidectomy specimens and there clinic pathological correlation. Methods: This is a prospective study of 100 cases of thyroidectomy between July 2018 and June 2019. A detailed gross examination and histomorphological study with clinical correlation was done. Results: Females preponderance was noted (86% cases) with M: F ratio of 1:5. Over 90% of cases were in the age group 20-60 years with peak incidence in the 4th decade of life (32%). Neoplasms were present only in 21% of cases, which included malignant neoplasms in 16.4% cases. Adenomatoid goiter was the most common lesion followed by papillary carcinoma, Hashimoto thyroiditis, follicular adenoma, follicular carcinoma, hurthle cell adenoma, medullary carcinoma and secondaries. Ancillary pathologies in adenomatoid goiter included follicular adenomas (4.2%), hurthle cell adenoma (0.7%), papillary carcinomas (8.1%) and follicular carcinomas (0.4%). Conclusion: Thyroid lesions requiring surgical excision were more common in females than males. Patients affected had a wide age range between 17 to 78 years of age, with a peak incidence in the 4th decade of life (32%). Careful gross and microscopic examination of thyroidectomy specimens with clinicopathological correlation is necessary to distinguish benign from malignant lesions which helps in further management.
Sandeep Yadav, Prajna KS, Gopinath Rajesh. Histomorphological study of patterns of thyroid lesions in a tertiary care centre. Int. J. Pathol. Res. 2020;2(1):05-09.